Anti-C1GALT1C1 antibody (30-190) (STJ29727)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal C1GALT1C1 (30-190) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | C1GALT1C1 |
| Gene ID | 29071 |
| Uniprot ID | C1GLC_HUMAN |
| Immunogen Region | 30-190 |
| Immunogen Sequence | IGHGNRMHHHEHHHLQAPNK EDILKISEDERMELSKSFRV YCIILVKPKDVSLWAAVKET WTKHCDKAEFFSSENVKVFE SINMDTNDMWLMMRKAYKYA FDKYRDQYNWFFLARPTTFA IIENLKYFLLKKDPSQPFYL GHTIKSGDLEYVGMEGGIVL S |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 30-190 of human C1GALT1C1 (NP_689905.1). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. Abundantly expressed in salivary gland, stomach, small intestine, kidney, and testis and at intermediate levels in whole brain, cerebellum, spinal cord, thymus, spleen, trachea, lung, pancreas, ovary, and uterus. |
| Function | Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1). |
| Protein Name | C1galt1-Specific Chaperone 1C38h2-Like Protein 1C38h2-L1Core 1 Beta1 -3-Galactosyltransferase 2C1gal-T2C1galt2Core 1 Beta3-Gal-T2Core 1 Beta3-Galactosyltransferase-Specific Molecular Chaperone |
| Database Links | Reactome: R-HSA-5083632Reactome: R-HSA-913709 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-C1galt1-Specific Chaperone 1 antibodyAnti-C38h2-Like Protein 1 antibodyAnti-C38h2-L1 antibodyAnti-Core 1 Beta1 -3-Galactosyltransferase 2 antibodyAnti-C1gal-T2 antibodyAnti-C1galt2 antibodyAnti-Core 1 Beta3-Gal-T2 antibodyAnti-Core 1 Beta3-Galactosyltransferase-Specific Molecular Chaperone antibodyAnti-C1GALT1C1 antibodyAnti-COSMC antibodyAnti-HSPC067 antibodyAnti-MSTP143 antibodyAnti-UNQ273 antibodyAnti-PRO310 antibody |
Information sourced from Uniprot.org