| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | C1GALT1C1 |
| Gene ID: | 29071 |
| Uniprot ID: | C1GLC_HUMAN |
| Immunogen Region: | 30-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-190 of human C1GALT1C1 (NP_689905.1). |
| Immunogen Sequence: | IGHGNRMHHHEHHHLQAPNK EDILKISEDERMELSKSFRV YCIILVKPKDVSLWAAVKET WTKHCDKAEFFSSENVKVFE SINMDTNDMWLMMRKAYKYA FDKYRDQYNWFFLARPTTFA IIENLKYFLLKKDPSQPFYL GHTIKSGDLEYVGMEGGIVL S |
| Tissue Specificity | Ubiquitously expressed. Abundantly expressed in salivary gland, stomach, small intestine, kidney, and testis and at intermediate levels in whole brain, cerebellum, spinal cord, thymus, spleen, trachea, lung, pancreas, ovary, and uterus. |
| Function | Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1). |
| Protein Name | C1galt1-Specific Chaperone 1 C38h2-Like Protein 1 C38h2-L1 Core 1 Beta1 -3-Galactosyltransferase 2 C1gal-T2 C1galt2 Core 1 Beta3-Gal-T2 Core 1 Beta3-Galactosyltransferase-Specific Molecular Chaperone |
| Database Links | Reactome: R-HSA-5083632 Reactome: R-HSA-913709 |
| Cellular Localisation | Membrane Single-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-C1galt1-Specific Chaperone 1 antibody Anti-C38h2-Like Protein 1 antibody Anti-C38h2-L1 antibody Anti-Core 1 Beta1 -3-Galactosyltransferase 2 antibody Anti-C1gal-T2 antibody Anti-C1galt2 antibody Anti-Core 1 Beta3-Gal-T2 antibody Anti-Core 1 Beta3-Galactosyltransferase-Specific Molecular Chaperone antibody Anti-C1GALT1C1 antibody Anti-COSMC antibody Anti-HSPC067 antibody Anti-MSTP143 antibody Anti-UNQ273 antibody Anti-PRO310 antibody |
Information sourced from Uniprot.org