Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Uncharacterized protein C12orf40 (350-400 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
REDIC1 |
Gene ID: |
283461 |
Uniprot ID: |
RDIC1_HUMAN |
Immunogen Region: |
350-400 aa |
Specificity: |
This antibody detects endogenous levels of CL040 at Human |
Immunogen: |
Synthesized peptide derived from the human CL040 at the amino acid range 350-400 |
Protein Name | Regulator Of Dna Class I Crossover Intermediates 1 |
Cellular Localisation | ChromosomeIn Pachytene SpermatocytesLocalized Along Autosomal Axes And The Synapsed Pseudoautosomal Region On Sex ChromosomesDecreasing Rapidly After Early PachyteneBy Mid- Or Late PachyteneAnd Disappearing In The Diplotene StageAlso Detected On The Paired Regions Of Homologous Chromosomes In Zygotene And Pachytene OocytesColocalizing With Msh4Chromosomal Localization Of Redic1 Is Mainly Dependent On Meiotic Dna Double-Strand Breaks (Dsbs) And Interhomolog Strand InvasionIn Spermatocytes From Early Zygotene To Early PachyteneMore Than 90% Of Redic1 Foci Colocalize With Rpa2Probably Localizes First To Recombination Intermediates And Later Colocalizes With Mlh1 At Crossover Sites |
Alternative Antibody Names | Anti-Regulator Of Dna Class I Crossover Intermediates 1 antibodyAnti-REDIC1 antibodyAnti-C12orf40 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance