Anti-C-peptide antibody (12-30a) [9101] (STJ400017)

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STJ400017
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Host: Mouse
Applications: FIA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-C-peptide (12-30a) for use in FIA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : 9101
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
Concentration: 5.0 mg/ml (+/-10 %)
Storage Instruction: Store at 2–8 °C, and do not freeze.
Immunogen Region: 12-30a
Specificity: Antibody recognizes human C-peptide. Human proinsulin (recombinant) 0.93 %
Immunogen: The binding site is located within the range 12-30, with the most critical amino acids for binding being LEGSL (26-30). There was no binding signal detected with peptides without the amino acid L (26).
Background C-peptide is produced when proinsulin is split into insulin and C-peptide. They split before proinsulin is released from endocytic vesicles within the pancreas-one C-peptide for each insulin molecule. When a patient has newly diagnosed type 1 or type 2 diabetes, C-peptide can be used to help determine how much insulin the patient s pancreas is still producing. C-peptide measurements also can be used in conjunction with insulin and glucose levels to help diagnose the cause of documented hypoglycemia and to monitor its treatment.

Information sourced from Uniprot.org