| Host: | Mouse |
| Applications: | FIA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-C-peptide (12-30a) for use in FIA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 9101 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | Store at 2–8 °C, and do not freeze. |
| Immunogen Region: | 12-30a |
| Specificity: | Antibody recognizes human C-peptide. Human proinsulin (recombinant) 0.93 % |
| Immunogen: | The binding site is located within the range 12-30, with the most critical amino acids for binding being LEGSL (26-30). There was no binding signal detected with peptides without the amino acid L (26). |
| Background | C-peptide is produced when proinsulin is split into insulin and C-peptide. They split before proinsulin is released from endocytic vesicles within the pancreas-one C-peptide for each insulin molecule. When a patient has newly diagnosed type 1 or type 2 diabetes, C-peptide can be used to help determine how much insulin the patient s pancreas is still producing. C-peptide measurements also can be used in conjunction with insulin and glucose levels to help diagnose the cause of documented hypoglycemia and to monitor its treatment. |
Information sourced from Uniprot.org

