Anti-c-Myc antibody [IHC448] (STJA0042138)

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STJA0042138
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Short Description :Rabbit monoclonal anti-c-Myc for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-p
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :IHC448
Isotype:IgG
Conjugation:Unconjugated
Formulation:Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage Instruction:Store at 2-8°C for up to 1 year. Do not freeze.
Specificity:Tested and validated on tonsil tissue.
Background c-Myc is a phosphoprotein involved with cell proliferation and differentiation. It is a useful marker for differentiation between Burkitt s lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) since, despite morphological similarities between the two B-cell lymphomas, Anti-c-Myc stains all BL and only a few DLBCL cases. A panel of antibodies against c-Myc, CD10, BCL2, and Ki-67 is useful for cases where Myc FISH analysis is warranted or can be omitted. Nuclear c-Myc overexpression is common in luminal cells of prostate intraepithelial neoplasia, many primary carcinomas, and metastatic disease.

Information sourced from Uniprot.org

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