| Tissue Specificity | Detected on T-cells, natural killer cells, dendritic cells and macrophages (at protein level). Ubiquitous. Highly expressed in heart, pancreas and lung, Moderately expressed in placenta, liver and muscle. |
| Post Translational Modifications | N-glycosylated. |
| Function | Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |
| Protein Name | Butyrophilin Subfamily 3 Member A1Cd Antigen Cd277 |
| Database Links | Reactome: R-HSA-8851680 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Butyrophilin Subfamily 3 Member A1 antibodyAnti-Cd Antigen Cd277 antibodyAnti-BTN3A1 antibodyAnti-BTF5 antibody |
Information sourced from Uniprot.org
