| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Butyrophilin subfamily 3 member A1 and Butyrophilin subfamily 3 member A2 and Butyrophilin subfamily 3 member A3 (41-90 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research application |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200 ELISA 1:10000-20000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BTN3A1 BTN3A2 11119 11118 10384 BT3A1_HUMAN BT3A2_HUMAN BT3A3_HUMAN |
| Immunogen Region: | 41-90 aa |
| Specificity: | The antibody detects endogenous BTN3A1/2/3 |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 41-90 |
| Post Translational Modifications | N-glycosylated. |
| Function | Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |
| Protein Name | Butyrophilin Subfamily 3 Member A1 Cd Antigen Cd277 |
| Database Links | Reactome: R-HSA-8851680 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Butyrophilin Subfamily 3 Member A1 antibody Anti-Cd Antigen Cd277 antibody Anti-BTN3A1 antibody Anti-BTF5 antibody |
Information sourced from Uniprot.org