Anti-BTF3 antibody (2-105 aa) [R01-2B7] (STJA0011049)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human BTF3
General Information
| Short Description | Rabbit monoclonal anti-BTF3 (2-105 aa) for use in WB, IHC-P and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-2B7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | BTF3 |
| Gene ID | 689 |
| Uniprot ID | BTF3_HUMAN |
| Immunogen | Recombinant protein of human BTF3 |
| Immunogen Region | 2-105 aa |
Additional Info
| Function | When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription. |
| Protein Name | Transcription Factor Btf3Nascent Polypeptide-Associated Complex Subunit BetaNac-BetaRna Polymerase B Transcription Factor 3 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusThe Heterodimer With Naca Is Cytoplasmic |
| Alternative Antibody Names | Anti-Transcription Factor Btf3 antibodyAnti-Nascent Polypeptide-Associated Complex Subunit Beta antibodyAnti-Nac-Beta antibodyAnti-Rna Polymerase B Transcription Factor 3 antibodyAnti-BTF3 antibodyAnti-NACB antibodyAnti-OK antibodyAnti-SW-cl.8 antibody |
Information sourced from Uniprot.org