Anti-BTC antibody (32-178) (STJ22842)

Name: Anti-BTC antibody (32-178) (STJ22842)
SKU: STJ22842
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ22842

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Short Description	Rabbit polyclonal BTC (32-178) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	BTC
Gene ID	685
Uniprot ID	BTC_HUMAN
Immunogen Region	32-178
Immunogen Sequence	DGNSTRSPETNGLLCGDPEE NCAATTTQSKRKGHFSRCPK QYKHYCIKGRCRFVVAEQTP SCVCDEGYIGARCERVDLFY LRGDRGQILVICLIAVMVVF IILVIGVCTCCHPLRKRRKR KKKEEEMETLGKDITPINED IEETNIA
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 32-178 of human BTC (NP_001720.1).

Tissue Specificity	Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
Function	Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Protein Name	Probetacellulin Cleaved Into - Betacellulin Btc
Database Links	Reactome: R-HSA-1227986 Reactome: R-HSA-1236394 Reactome: R-HSA-1250196 Reactome: R-HSA-1250342 Reactome: R-HSA-1250347 Reactome: R-HSA-1251985 Reactome: R-HSA-1257604 Reactome: R-HSA-177929 Reactome: R-HSA-179812 Reactome: R-HSA-180292 Reactome: R-HSA-180336 Reactome: R-HSA-182971 Reactome: R-HSA-1963640 Reactome: R-HSA-1963642 Reactome: R-HSA-212718 Reactome: R-HSA-2219530 Reactome: R-HSA-5638303 Reactome: R-HSA-5673001 Reactome: R-HSA-6785631 Reactome: R-HSA-6811558 Reactome: R-HSA-8847993 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-8863795 Reactome: R-HSA-9009391 Reactome: R-HSA-9634638 Reactome: R-HSA-9664565 Reactome: R-HSA-9665686
Cellular Localisation	Betacellulin: Secreted Extracellular Space Probetacellulin: Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Probetacellulin Cleaved Into - Betacellulin antibody Anti-Btc antibody Anti-BTC antibody

Information sourced from Uniprot.org