| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
BTBD10 |
| Gene ID: |
84280 |
| Uniprot ID: |
BTBDA_HUMAN |
| Immunogen Region: |
1-180 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human BTBD10 (NP_115696.2). |
| Immunogen Sequence: |
MAGRPHPYDGNSSDPENWDR KLHSRPRKLYKHSSTSSRIA KGGVDHTKMSLHGASGGHER SRDRRRSSDRSRDSSHERTE SQLTPCIRNVTSPTRQHHVE REKDHSSSRPSSPRPQKASP NGSISSAGNSSRNSSQSSSD GSCKTAGEMVFVYENAKEGA RNIRTSERVTLIVDNTRFVV |
| Tissue Specificity | Ubiquitously expressed. Highly expressed in adult brain, testis, aorta and small intestine and weakly expressed in the heart, lung, liver, kidney, pancreas, spleen, thymus, prostate, ovary and colon. Down-regulated in glioma. |
| Function | Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and accelerating the growth of pancreatic beta cells. |
| Protein Name | Btb/Poz Domain-Containing Protein 10Glucose Metabolism-Related Protein 1 |
| Cellular Localisation | NucleusCytoplasmColocalizes With Kctd20 In Filamentous Structures |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein 10 antibodyAnti-Glucose Metabolism-Related Protein 1 antibodyAnti-BTBD10 antibodyAnti-GMRP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
