| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Bruno-like 5 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Approx 55kDa band observed in Human Heart lysates (calculated MW of 52.4kDa according to NP_068757.2). Recommended concentration: 1-3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CELF5 |
| Gene ID: | 60680 |
| Uniprot ID: | CELF5_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_068757.2 |
| Immunogen Sequence: | EPPGGQPDGMKD |
| Function | RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. |
| Protein Name | Cugbp Elav-Like Family Member 5Celf-5Bruno-Like Protein 5Cug-Bp- And Etr-3-Like Factor 5Rna-Binding Protein Brunol-5 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Cugbp Elav-Like Family Member 5 antibodyAnti-Celf-5 antibodyAnti-Bruno-Like Protein 5 antibodyAnti-Cug-Bp- And Etr-3-Like Factor 5 antibodyAnti-Rna-Binding Protein Brunol-5 antibodyAnti-CELF5 antibodyAnti-BRUNOL5 antibody |
Information sourced from Uniprot.org