| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BRI3 |
| Gene ID: | 25798 |
| Uniprot ID: | BRI3_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BRI3 (NP_056194.1). |
| Immunogen Sequence: | MDHKPLLQERPPAYNLEAGQ GDYACGPHGYGAIPAAPPPP PYPYLVTGIPTHHPRVYNIH SRTVTRYPANSIVVVGGCPV CRVGVLEDCFTFLGIFLAII |
| Function | Participates in tumor necrosis factor-alpha (TNF)-induced cell death. May be a target of Wnt/beta-catenin signaling in the liver. |
| Protein Name | Membrane Protein Bri3Brain Protein I3Prgr2 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinIsoform 1: CytoplasmPerinuclear RegionCo-Localizes With Mgat1 And Ifitm3 At The Perinuclear RegionIsoform 2: CytoplasmNucleusDiffuse Localization In The Cytoplasm And Nucleus |
| Alternative Antibody Names | Anti-Membrane Protein Bri3 antibodyAnti-Brain Protein I3 antibodyAnti-Prgr2 antibodyAnti-BRI3 antibody |
Information sourced from Uniprot.org