Anti-BRF2 antibody (C-Term) (STJ70258)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-BRF2 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 50kDa band observed in HeLa lysates (predicted MW of 48kDa according to NP_060780). Recommended for use at 1-3ยตg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | BRF2 |
| Gene ID | 55290 |
| Uniprot ID | BRF2_HUMAN |
| Accession Number | NP_060780.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | QAARQAATSVPNPP |
Additional Info
| Function | General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression.functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress. |
| Protein Name | Transcription Factor Iiib 50 Kda SubunitTfiiib50Htfiiib50B-Related Factor 2Brf-2Hbrfu |
| Database Links | Reactome: R-HSA-749476Reactome: R-HSA-76071 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Iiib 50 Kda Subunit antibodyAnti-Tfiiib50 antibodyAnti-Htfiiib50 antibodyAnti-B-Related Factor 2 antibodyAnti-Brf-2 antibodyAnti-Hbrfu antibodyAnti-BRF2 antibodyAnti-BRFU antibodyAnti-PRO1470 antibody |
Information sourced from Uniprot.org