| Tissue Specificity | Ubiquitously expressed. |
| Post Translational Modifications | Ubiquitinated by NEDD4, NEDD4L and ITCH.mono- and polyubiquitinated forms are detected. |
| Function | Involved in DNA damage response.activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress. Plays a role in regulating mitochondrial function and cell proliferation. Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors. |
| Protein Name | Brca1-Associated Atm Activator 1Brca1-Associated Protein Required For Atm Activation Protein 1 |
| Cellular Localisation | NucleusCytoplasmPresent At Double Strand Breaks (Dsbs)Following Ionizing Radiation TreatmentThe Ubiquitinated Form Localizes In The Nucleus In A Ndfip1-Dependent Manner |
| Alternative Antibody Names | Anti-Brca1-Associated Atm Activator 1 antibodyAnti-Brca1-Associated Protein Required For Atm Activation Protein 1 antibodyAnti-BRAT1 antibodyAnti-BAAT1 antibodyAnti-C7orf27 antibody |
Information sourced from Uniprot.org
