Anti-BPGM antibody (STJA0008337)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human BPGM
General Information
| Short Description | Rabbit polyclonal anti-Bisphosphoglycerate mutase for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BPGM |
| Gene ID | 669 |
| Uniprot ID | PMGE_HUMAN |
| Immunogen | Synthesized peptide derived from human BPGM |
| Specificity | This antibody detects endogenous levels of BPGM at Human, Mouse |
Additional Info
| Post Translational Modifications | Glycation of Lys-159 in diabetic patients inactivates the enzyme. |
| Function | Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase activity. |
| Protein Name | Bisphosphoglycerate MutaseBpgm2 -3-Bisphosphoglycerate Mutase - Erythrocyte2 -3-Bisphosphoglycerate Synthase2 -3-Diphosphoglycerate MutaseDpgmBpg-Dependent Pgam |
| Database Links | Reactome: R-HSA-70171 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Bisphosphoglycerate Mutase antibodyAnti-Bpgm antibodyAnti-2 -3-Bisphosphoglycerate Mutase - Erythrocyte antibodyAnti-2 -3-Bisphosphoglycerate Synthase antibodyAnti-2 -3-Diphosphoglycerate Mutase antibodyAnti-Dpgm antibodyAnti-Bpg-Dependent Pgam antibodyAnti-BPGM antibody |
Information sourced from Uniprot.org