Anti-BORCS5 antibody (9-59 aa) (STJ195172)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human L12R1 at the amino acid range 9-59
STJ195172
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General Information

Short DescriptionRabbit polyclonal anti-BLOC-1-related complex subunit 5 (9-59 aa) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
IHC-P 1:50-300
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolBORCS5
Gene ID118426
Uniprot IDBORC5_HUMAN
ImmunogenSynthesized peptide derived from the human L12R1 at the amino acid range 9-59
Immunogen Region9-59 aa
SpecificityThis antibody detects endogenous levels of L12R1 at Human/Mouse

Additional Info

Post Translational Modifications Myristoylation at Gly-2 mediates attachment to lysosome membranes.
Function As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility.
Protein Name Bloc-1-Related Complex Subunit 5
Loss Of Heterozygosity 12 Chromosomal Region 1
Myristoylated Lysosomal Protein
Myrlysin
Database Links
Cellular Localisation Lysosome Membrane
Lipid-Anchor
Cytoplasmic Side
Alternative Antibody Names Anti-Bloc-1-Related Complex Subunit 5 antibody
Anti-Loss Of Heterozygosity 12 Chromosomal Region 1 antibody
Anti-Myristoylated Lysosomal Protein antibody
Anti-Myrlysin antibody
Anti-BORCS5 antibody
Anti-LOH12CR1 antibody

Information sourced from Uniprot.org

Citations

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