| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-BLOC-1-related complex subunit 5 (9-59 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BORCS5 |
| Gene ID: | 118426 |
| Uniprot ID: | BORC5_HUMAN |
| Immunogen Region: | 9-59 aa |
| Specificity: | This antibody detects endogenous levels of L12R1 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human L12R1 at the amino acid range 9-59 |
| Post Translational Modifications | Myristoylation at Gly-2 mediates attachment to lysosome membranes. |
| Function | As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility. |
| Protein Name | Bloc-1-Related Complex Subunit 5Loss Of Heterozygosity 12 Chromosomal Region 1Myristoylated Lysosomal ProteinMyrlysin |
| Cellular Localisation | Lysosome MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Bloc-1-Related Complex Subunit 5 antibodyAnti-Loss Of Heterozygosity 12 Chromosomal Region 1 antibodyAnti-Myristoylated Lysosomal Protein antibodyAnti-Myrlysin antibodyAnti-BORCS5 antibodyAnti-LOH12CR1 antibody |
Information sourced from Uniprot.org
