• Western blot analysis of various lysates, using BMPR1B Rabbit polyclonal antibody (STJ11104436) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-BMPR1B antibody (450-532) (STJ11104436)

SKU:
STJ11104436

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Bone Morphogenetic Protein Receptor Type-1b (450-532) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BMPR1B
Gene ID: 658
Uniprot ID: BMR1B_HUMAN
Immunogen Region: 450-532
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 450-532 of human BMPR1B (NP_001243722.1).
Immunogen Sequence: VEEYQLPYHDLVPSDPSYED MREIVCIKKLRPSFPNRWSS DECLRQMGKLMTECWAHNPA SRLTALRVKKTLAKMSESQD IKL
Post Translational Modifications Autophosphorylated.
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.
Protein Name Bone Morphogenetic Protein Receptor Type-1b
Bmp Type-1b Receptor
Bmpr-1b
Cd Antigen Cdw293
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Bone Morphogenetic Protein Receptor Type-1b antibody
Anti-Bmp Type-1b Receptor antibody
Anti-Bmpr-1b antibody
Anti-Cd Antigen Cdw293 antibody
Anti-BMPR1B antibody

Information sourced from Uniprot.org

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