| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Golgin-45 (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BLZF1 |
| Gene ID: | 8548 |
| Uniprot ID: | GO45_HUMAN |
| Immunogen Region: | 10-59 aa |
| Specificity: | Golgin 45 Polyclonal Antibody detects endogenous levels of Golgin 45 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human BLZF1 at the amino acid range 10-59 |
| Post Translational Modifications | ADP-ribosylated by tankyrase TNKS and TNKS2. Poly-ADP-ribosylated protein is recognized by RNF146, followed by ubiquitination. Ubiquitinated by RNF146 when poly-ADP-ribosylated, leading to its degradation. |
| Function | Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface. |
| Protein Name | Golgin-45Basic Leucine Zipper Nuclear Factor 1Jem-1P45 Basic Leucine-Zipper Nuclear Factor |
| Database Links | Reactome: R-HSA-162658 |
| Cellular Localisation | Golgi Apparatus MembraneIsoform 1: NucleusDetected In The Nucleus Upon Heterologous ExpressionNot Detected In The CytoplasmIsoform 2: CytoplasmNot Detected In The Nucleus |
| Alternative Antibody Names | Anti-Golgin-45 antibodyAnti-Basic Leucine Zipper Nuclear Factor 1 antibodyAnti-Jem-1 antibodyAnti-P45 Basic Leucine-Zipper Nuclear Factor antibodyAnti-BLZF1 antibodyAnti-JEM1 antibody |
Information sourced from Uniprot.org