Anti-BLZF1 antibody (1-400) (STJ28513)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal BLZF1 (1-400) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BLZF1 |
| Gene ID | 8548 |
| Uniprot ID | GO45_HUMAN |
| Immunogen Region | 1-400 |
| Immunogen Sequence | MTTKNLETKVTVTSSPIRGA GDGMETEEPPKSVEVTSGVQ SRKHHSLQSPWKKAVPSESP GVLQLGKMLTEKAMEVKAVR ILVPKAAITHDIPNKNTKVK SLGHHKGEFLGQSEGVIEPN KELSEVKNVLEKLKNSERRL LQDKEGLSNQLRVQTEVNRE LKKLLVASVGDDLQYHFERL AREKNQLILENEALGRNTAQ LSEQLERMSIQCDVWRSKFL ASRVMADELTNSRAALQRQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-400 of human BLZF1 (NP_003657.1). |
Additional Info
| Tissue Specificity | Detected in adrenal gland. |
| Post Translational Modifications | ADP-ribosylated by tankyrase TNKS and TNKS2. Poly-ADP-ribosylated protein is recognized by RNF146, followed by ubiquitination. Ubiquitinated by RNF146 when poly-ADP-ribosylated, leading to its degradation. |
| Function | Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface. |
| Protein Name | Golgin-45Basic Leucine Zipper Nuclear Factor 1Jem-1P45 Basic Leucine-Zipper Nuclear Factor |
| Database Links | Reactome: R-HSA-162658 |
| Cellular Localisation | Golgi Apparatus MembraneIsoform 1: NucleusDetected In The Nucleus Upon Heterologous ExpressionNot Detected In The CytoplasmIsoform 2: CytoplasmNot Detected In The Nucleus |
| Alternative Antibody Names | Anti-Golgin-45 antibodyAnti-Basic Leucine Zipper Nuclear Factor 1 antibodyAnti-Jem-1 antibodyAnti-P45 Basic Leucine-Zipper Nuclear Factor antibodyAnti-BLZF1 antibodyAnti-JEM1 antibody |
Information sourced from Uniprot.org