• Immunofluorescence analysis of U-2 OS cells using BLOC1S3 Rabbit polyclonal antibody (STJ119421) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of NIH-3T3 cells using BLOC1S3 Rabbit polyclonal antibody (STJ119421) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of C6 cells using BLOC1S3 Rabbit polyclonal antibody (STJ119421) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunohistochemistry analysis of BLOC1S3 in paraffin-embedded mouse testis using BLOC1S3 Rabbit polyclonal antibody (STJ119421) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of BLOC1S3 in paraffin-embedded human colon using BLOC1S3 Rabbit polyclonal antibody (STJ119421) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-BLOC1S3 antibody (1-202) (STJ119421)

SKU:
STJ119421

£112.50 - £524.50
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Host: Rabbit
Applications: IHC-P/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: IHC-P:1:50-1:200
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BLOC1S3
Gene ID: 388552
Uniprot ID: BL1S3_HUMAN
Immunogen Region: 1-202
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human BLOC1S3 (NP_997715.1).
Immunogen Sequence: MASQGRRRRPLRRPETVVPG EATETDSERSASSSEEEELY LGPSGPTRGRPTGLRVAGEA AETDSEPEPEPEPTAAPRDL PPLVVQRESAEEAWGTEEAP APAPARSLLQLRLAESQARL DHDVAAAVSGVYRRAGRDVA ALASRLAAAQAAGLAAAHSV RLARGDLCALAERLDIVAGC RLLPDIRGVPGTEPEKDPGP RA
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
Protein Name Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 3
Bloc-1 Subunit 3
Database Links Reactome: R-HSA-432722
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 3 antibody
Anti-Bloc-1 Subunit 3 antibody
Anti-BLOC1S3 antibody
Anti-BLOS3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance