Anti-BHMT antibody (300-406) [S9MR] (STJ11102269)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal BHMT (300-406) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S9MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BHMT |
| Gene ID | 635 |
| Uniprot ID | BHMT1_HUMAN |
| Immunogen Region | 300-406 |
| Immunogen Sequence | CGFEPYHIRAIAEELAPERG FLPPASEKHGSWGSGLDMHT KPWVRARARKEYWENLRIAS GRPYNPSMSKPDGWGVTKGT AELMQQKEATTEQQLKELFE KQKFKSQ |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 300-406 of human BHMT (Q93088). |
Additional Info
| Tissue Specificity | Found exclusively in liver and kidney. |
| Function | Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. |
| Protein Name | Betaine--Homocysteine S-Methyltransferase 1 |
| Database Links | Reactome: R-HSA-1614635Reactome: R-HSA-6798163 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly Localized In The Cytoplasm With A Small Fraction Detected In The NucleusTranslocates Into The Nucleus Upon Oxidative Stress |
| Alternative Antibody Names | Anti-Betaine--Homocysteine S-Methyltransferase 1 antibodyAnti-BHMT antibody |
Information sourced from Uniprot.org