Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-BHMT (300-406) is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S9MR |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
BHMT |
Gene ID: |
635 |
Uniprot ID: |
BHMT1_HUMAN |
Immunogen Region: |
300-406 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 300-406 of human BHMT (Q93088). |
Immunogen Sequence: |
CGFEPYHIRAIAEELAPERG FLPPASEKHGSWGSGLDMHT KPWVRARARKEYWENLRIAS GRPYNPSMSKPDGWGVTKGT AELMQQKEATTEQQLKELFE KQKFKSQ |
Tissue Specificity | Found exclusively in liver and kidney. |
Function | Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. |
Protein Name | Betaine--Homocysteine S-Methyltransferase 1 |
Database Links | Reactome: R-HSA-1614635Reactome: R-HSA-6798163 |
Cellular Localisation | CytoplasmCytosolNucleusPredominantly Localized In The Cytoplasm With A Small Fraction Detected In The NucleusTranslocates Into The Nucleus Upon Oxidative Stress |
Alternative Antibody Names | Anti-Betaine--Homocysteine S-Methyltransferase 1 antibodyAnti-BHMT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance