| Tissue Specificity | Expressed at high levels in testis. Also expressed in pancreas, uterus and lung and salivary gland. |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Glycosyltransferase that catalyzes the transfer of carbohydrates to H antigen, forming the antigenic structures of the ABO blood group. |
| Protein Name | Histo-Blood Group Abo System TransferaseFucosylglycoprotein 3-Alpha-GalactosyltransferaseFucosylglycoprotein Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-GalactosyltransferaseHisto-Blood Group A TransferaseA TransferaseHisto-Blood Group B TransferaseB TransferaseNagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form |
| Database Links | Reactome: R-HSA-9033807 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecretedMembrane-Bound Form In Trans Cisternae Of GolgiSecreted Into The Body Fluid |
| Alternative Antibody Names | Anti-Histo-Blood Group Abo System Transferase antibodyAnti-Fucosylglycoprotein 3-Alpha-Galactosyltransferase antibodyAnti-Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase antibodyAnti-Glycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase antibodyAnti-Glycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase antibodyAnti-Histo-Blood Group A Transferase antibodyAnti-A Transferase antibodyAnti-Histo-Blood Group B Transferase antibodyAnti-B Transferase antibodyAnti-Nagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form antibodyAnti-ABO antibody |
Information sourced from Uniprot.org
