Anti-BEX4 antibody (Internal Region) (STJ13100045)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from internal region of human BEX4 conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-BEX4 (Internal Region) for use in IHC and WB in Human and Marmoset samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Marmoset |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | BEX4 |
| Gene ID | 56271 |
| Uniprot ID | BEX4_HUMAN |
| Immunogen | A synthetic peptide from internal region of human BEX4 conjugated to blue carrier protein was used as the antigen. |
| Immunogen Region | Internal Region |
| Specificity | Specific for BEX4. |
Additional Info
| Post Translational Modifications | Ubiquitinated and degraded by the proteasome. |
| Function | May play a role in microtubule deacetylation by negatively regulating the SIRT2 deacetylase activity toward alpha-tubulin and thereby participate in the control of cell cycle progression and genomic stability. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates. |
| Protein Name | Protein Bex4Bex1-Like Protein 1Brain-Expressed X-Linked Protein 4Nerve Growth Factor Receptor-Associated Protein 3 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSpindle PoleNucleusAlso Localizes To Microtubules |
| Alternative Antibody Names | Anti-Protein Bex4 antibodyAnti-Bex1-Like Protein 1 antibodyAnti-Brain-Expressed X-Linked Protein 4 antibodyAnti-Nerve Growth Factor Receptor-Associated Protein 3 antibodyAnti-BEX4 antibodyAnti-BEXL1 antibodyAnti-NADE3 antibody |
Information sourced from Uniprot.org