| Post Translational Modifications | Phosphorylated. Phosphorylation of Ser-105 protects it from the proteasome. Ubiquitinated. Degraded by the proteasome. |
| Function | Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates. |
| Protein Name | Protein Bex1Brain-Expressed X-Linked Protein 1 HomologReduced Expression Protein 3Rex-3 |
| Cellular Localisation | NucleusCytoplasmShuttles Between The Cytoplasm And The NucleusPredominantly Nuclear |
| Alternative Antibody Names | Anti-Protein Bex1 antibodyAnti-Brain-Expressed X-Linked Protein 1 Homolog antibodyAnti-Reduced Expression Protein 3 antibodyAnti-Rex-3 antibodyAnti-Bex1 antibodyAnti-Rex3 antibody |
Information sourced from Uniprot.org
