Anti-Beta-galactosidase antibody [SRM14673] (STJ11109403)

SKU:
STJ11109403
£118.50 - £521.50
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Applications:WB/IHC-P/ELISA
Host:Rabbit
Reactivity:Human/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SRM14673
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity purification
Dilution Range:WB, 1:1000-1:5000
IHC-P, 1:50-1:200
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:GLB1
Gene ID:2720
Uniprot ID:BGAL_HUMAN
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity Detected in placenta (at protein level). Detected in fibroblasts and testis.
Function Isoform 1: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Isoform 2: Has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers.
Protein Name Beta-Galactosidase
Acid Beta-Galactosidase
Lactase
Elastin Receptor 1
Database Links Reactome: R-HSA-2022857
Reactome: R-HSA-2024096
Reactome: R-HSA-2206308
Reactome: R-HSA-4085001
Reactome: R-HSA-4341670
Reactome: R-HSA-6798695
Reactome: R-HSA-9840310
Cellular Localisation Isoform 1: Lysosome
Isoform 2: Cytoplasm
Perinuclear Region
Localized To The Perinuclear Area Of The Cytoplasm But Not To Lysosomes
Alternative Antibody Names Anti-Beta-Galactosidase antibody
Anti-Acid Beta-Galactosidase antibody
Anti-Lactase antibody
Anti-Elastin Receptor 1 antibody
Anti-GLB1 antibody
Anti-ELNR1 antibody

Information sourced from Uniprot.org