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Anti-beta-2-microglobulin antibody (65-79) (STJ72800)

STJ72800 (0. 03µg/ml) staining of Human Duodenum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-beta-2-microglobulin antibody (65-79) (STJ72800)

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STJ72800-100

£303.50

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General Information
Product Properties
Target Information
Additional Info
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Host:	Goat
Applications:	Pep-ELISA/WB
Reactivity:	Human/Cow
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-beta-2-microglobulin (65-79) is suitable for use in ELISA and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-0.03-0.1µg/ml ELISA-antibody detection limit dilution 1:32000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	B2M
Gene ID:	567
Uniprot ID:	B2MG_HUMAN
Immunogen Region:	65-79
Accession Number:	NP_004039.1
Immunogen Sequence:	RIEKVEHSDLSFSKD

Function	Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Protein Name	Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3
Database Links	Reactome: R-HSA-1236974 Reactome: R-HSA-1236977 Reactome: R-HSA-164940 Reactome: R-HSA-198933 Reactome: R-HSA-2172127 Reactome: R-HSA-2424491 Reactome: R-HSA-6798695 Reactome: R-HSA-877300 Reactome: R-HSA-9637628 Reactome: R-HSA-9705671 Reactome: R-HSA-977225 Reactome: R-HSA-983170
Cellular Localisation	Secreted Cell Surface Detected In Serum And Urine (Microbial Infection) In The Presence Of M Tuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface
Alternative Antibody Names	Anti-Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 antibody Anti-B2M antibody Anti-CDABP0092 antibody Anti-HDCMA22P antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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