• STJ72800 (0. 03µg/ml) staining of Human Duodenum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-beta-2-microglobulin antibody (65-79) (STJ72800)

SKU:
STJ72800-100

£312.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-beta-2-microglobulin (65-79) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:32000.
WB: Approx 12kDa band observed in Human Duodenum lysates (calculated MW of 13.7kDa according to NP_004039.1). Recommended concentration: 0.03-0.1µg/ml.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: B2M
Gene ID: 567
Uniprot ID: B2MG_HUMAN
Immunogen Region: 65-79
Accession Number: NP_004039.1
Immunogen Sequence: RIEKVEHSDLSFSKD
Function Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Protein Name Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3
Database Links Reactome: R-HSA-1236974
Reactome: R-HSA-1236977
Reactome: R-HSA-164940
Reactome: R-HSA-198933
Reactome: R-HSA-2172127
Reactome: R-HSA-2424491
Reactome: R-HSA-6798695
Reactome: R-HSA-877300
Reactome: R-HSA-9637628
Reactome: R-HSA-9705671
Reactome: R-HSA-977225
Reactome: R-HSA-983170
Cellular Localisation Secreted
Cell Surface
Detected In Serum And Urine
(Microbial Infection) In The Presence Of M
Tuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface
Alternative Antibody Names Anti-Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 antibody
Anti-B2M antibody
Anti-CDABP0092 antibody
Anti-HDCMA22P antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance