| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | D.melanogaster/Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-BEST4 (400-500) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.75-1.20 µg/µl |
| Dilution Range: | WB: 1:500-1:1, 000 DB: 1:2, 000 ELISA: 1:2, 000 IP: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | BEST4 |
| Gene ID: | 266675 |
| Uniprot ID: | BEST4_HUMAN |
| Immunogen Region: | 400-500 |
| Immunogen: | Synthetic peptide taken within amino acid region 400-500 on human Bestrophin 4 protein. |
| Tissue Specificity | Predominantly found in colon and the weakly in fetal brain, spinal cord, retina, lung, trachea, testis and placenta. |
| Function | Ligand-gated anion channel that allows the movement of anions across cell membranes when activated by Calcium (Ca2+). Mediates the movement of hydrogencarbonate and chloride. |
| Protein Name | Bestrophin-4 Vitelliform Macular Dystrophy 2-Like Protein 2 |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Bestrophin-4 antibody Anti-Vitelliform Macular Dystrophy 2-Like Protein 2 antibody Anti-BEST4 antibody Anti-VMD2L2 antibody |
Information sourced from Uniprot.org
