| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BDKRB2 |
| Gene ID: | 624 |
| Uniprot ID: | BKRB2_HUMAN |
| Immunogen Region: | 302-391 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 302-391 of human BDKRB2 (NP_000614.1). |
| Immunogen Sequence: | SSCQDERIIDVITQIASFMA YSNSCLNPLVYVIVGKRFRK KSWEVYQGVCQKGGCRSEPI QMENSMGTLRTSISVERQIH KLQDWAGSRQ |
| Tissue Specificity | Ubiquitous. Widespread in normal smooth muscle tissue and neurons. |
| Function | Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Protein Name | B2 Bradykinin ReceptorB2rBk-2 Receptor |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-B2 Bradykinin Receptor antibodyAnti-B2r antibodyAnti-Bk-2 Receptor antibodyAnti-BDKRB2 antibodyAnti-BKR2 antibody |
Information sourced from Uniprot.org