| Short Description : | Rabbit polyclonal BCS1L (33-240) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BCS1L |
| Gene ID: | 617 |
| Uniprot ID: | BCS1_HUMAN |
| Immunogen Region: | 33-240 |
| Immunogen Sequence: | RKGVQLGLVAFRRHYMITLE VPARDRSYAWLLSWLTRHST RTQHLSVETSYLQHESGRIS TKFEFVPSPGNHFIWYRGKW IRVERSREMQMIDLQTGTPW ESVTFTALGTDRKVFFNILE EARELALQQEEGKTVMYTAV GSEWRPFGYPRRRRPLNSVV LQQGLADRIVRDVQEFIDNP KWYTDRGIPYRRGYLLYGPP GCGKSSFI |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 33-240 of human BCS1L (NP_004319.1). |
| Tissue Specificity | Ubiquitous. |
| Function | Chaperone necessary for the incorporation of Rieske iron-sulfur protein UQCRFS1 into the mitochondrial respiratory chain complex III. Plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. |
| Protein Name | Mitochondrial Chaperone Bcs1H-Bcs1Bcs1-Like Protein |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9865881 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Chaperone Bcs1 antibodyAnti-H-Bcs1 antibodyAnti-Bcs1-Like Protein antibodyAnti-BCS1L antibodyAnti-BCS1 antibody |
Information sourced from Uniprot.org
