| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BCLAF1 |
| Gene ID: | 9774 |
| Uniprot ID: | BCLF1_HUMAN |
| Immunogen Region: | 330-552 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 330-552 of human BCLAF1 (NP_001070909.1). |
| Immunogen Sequence: | TAKTGKFLKSPPLHKNLDAR EKSTFREESPLRIKMIASDS HRPEVKLKMAPVPLDDSNRP ASLTKDRLLASTLVHSVKKE QEFRSIFDHIKLPQASKSTS ESFIQHIVSLVHHVKEQYFK SAAMTLNERFTSYQKATEEH STRQKSPEIHRRIDISPSTL RKHTRLAGEERVFKEENQKG DKKLRCDSADLRHDIDRRRK ERSKERGDSKGSRESSGSRK QEK |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Citrullinated by PADI4. |
| Function | Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. |
| Protein Name | Bcl-2-Associated Transcription Factor 1BtfBclaf1 And Thrap3 Family Member 1 |
| Cellular Localisation | CytoplasmNucleusNucleus SpeckleNucleoplasm |
| Alternative Antibody Names | Anti-Bcl-2-Associated Transcription Factor 1 antibodyAnti-Btf antibodyAnti-Bclaf1 And Thrap3 Family Member 1 antibodyAnti-BCLAF1 antibodyAnti-BTF antibodyAnti-KIAA0164 antibody |
Information sourced from Uniprot.org