Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Bcl-2-like protein 2 (131-180 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | BCL2L2 |
Gene ID: | 599 |
Uniprot ID: | B2CL2_HUMAN |
Immunogen Region: | 131-180 aa |
Specificity: | Bcl-w Polyclonal Antibody detects endogenous levels of Bcl-w protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human BCLW at the amino acid range 131-180 |
Function | Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. |
Protein Name | Bcl-2-Like Protein 2Bcl2-L-2Apoptosis Regulator Bcl-W |
Cellular Localisation | Mitochondrion MembranePeripheral Membrane ProteinLoosely Associated With The Mitochondrial Membrane In Healthy CellsDuring ApoptosisTightly Bound To The Membrane |
Alternative Antibody Names | Anti-Bcl-2-Like Protein 2 antibodyAnti-Bcl2-L-2 antibodyAnti-Apoptosis Regulator Bcl-W antibodyAnti-BCL2L2 antibodyAnti-BCLW antibodyAnti-KIAA0271 antibody |
Information sourced from Uniprot.org