Anti-BAZ2B antibody (C-Term) (STJ70302)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-BAZ2B (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Preliminary experiments gave an approx 35kDa band in Testis and Brain lysates after 0.3ยตg/ml antibody staining. Please note that currently we cannot find an explanation in the literatur |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | BAZ2B |
| Gene ID | 29994 |
| Uniprot ID | BAZ2B_HUMAN |
| Accession Number | NP_038478.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | YFEKKWTDTFKVS |
Additional Info
| Function | Regulatory subunit of the ATP-dependent BRF-1 and BRF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. The BRF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the BRF-5 ISWI chromatin remodeling complex. Chromatin reader protein, which may play a role in transcriptional regulation via interaction with ISWI. Involved in positively modulating the rate of age-related behavioral deterioration. Represses the expression of mitochondrial function-related genes, perhaps by occupying their promoter regions, working in concert with histone methyltransferase EHMT1. |
| Protein Name | Bromodomain Adjacent To Zinc Finger Domain Protein 2bHwalp4 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Bromodomain Adjacent To Zinc Finger Domain Protein 2b antibodyAnti-Hwalp4 antibodyAnti-BAZ2B antibodyAnti-KIAA1476 antibody |
Information sourced from Uniprot.org