| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BAG4 (1-100) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BAG4 |
| Gene ID: |
9530 |
| Uniprot ID: |
BAG4_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BAG4 (NP_001191807.1). |
| Immunogen Sequence: |
MSALRRSGYGPSDGPSYGRY YGPGGGDVPVHPPPPLYPLR PEPPQPPISWRVRGGGPAET TWLGEGGGGDGYYPSGGAWP EPGRAGGSHQSLNSYTNGAY |
| Tissue Specificity | Ubiquitous. |
| Function | Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria. |
| Protein Name | Bag Family Molecular Chaperone Regulator 4Bag-4Bcl-2-Associated Athanogene 4Silencer Of Death Domains |
| Database Links | Reactome: R-HSA-3371453Reactome: R-HSA-5655302Reactome: R-HSA-75893Reactome: R-HSA-8853336 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Bag Family Molecular Chaperone Regulator 4 antibodyAnti-Bag-4 antibodyAnti-Bcl-2-Associated Athanogene 4 antibodyAnti-Silencer Of Death Domains antibodyAnti-BAG4 antibodyAnti-SODD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
