Anti-B7-H4 antibody (Internal) (STJ71250)

SKU:
STJ71250-100
£312.50
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Host: Goat
Applications: Pep-ELISA/WB/IF/FC
Reactivity: Human/Mouse/Rat/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-B7-H4 (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:64000.
WB: Approx 26+21kDa bands observed in HEK293 cell lysates, which were both successfully blocked by incubation with the immunizing peptide. An approx 26kDa and 21kDa band observed in Human
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: VTCN1
Gene ID: 79679
Uniprot ID: VTCN1_HUMAN
Immunogen Region: Internal
Accession Number: NP_078902.2; NP_001240778.1
Immunogen Sequence: SKGKGNANLEYK
Post Translational Modifications N-glycosylated.
Function Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Protein Name V-Set Domain-Containing T-Cell Activation Inhibitor 1
B7 Homolog 4
B7-H4
B7h.5
Immune Costimulatory Protein B7-H4
Protein B7s1
T-Cell Costimulatory Molecule B7x
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Expressed At The Cell Surface
A Soluble Form Has Also Been Detected
Alternative Antibody Names Anti-V-Set Domain-Containing T-Cell Activation Inhibitor 1 antibody
Anti-B7 Homolog 4 antibody
Anti-B7-H4 antibody
Anti-B7h.5 antibody
Anti-Immune Costimulatory Protein B7-H4 antibody
Anti-Protein B7s1 antibody
Anti-T-Cell Costimulatory Molecule B7x antibody
Anti-VTCN1 antibody
Anti-B7H4 antibody
Anti-UNQ659 antibody
Anti-PRO1291 antibody

Information sourced from Uniprot.org