Anti-B4GALT5 antibody (321-370 aa) (STJ96375)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human B4GALT5 at the amino acid range 321-370
General Information
| Short Description | Rabbit polyclonal anti-Beta-1, 4-galactosyltransferase 5 (321-370 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | B4GALT5 |
| Gene ID | 9334 |
| Uniprot ID | B4GT5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human B4GALT5 at the amino acid range 321-370 |
| Immunogen Region | 321-370 aa |
| Specificity | Beta-1, 4-Gal-T5 Polyclonal Antibody detects endogenous levels of Beta-1, 4-Gal-T5 protein. |
Additional Info
| Function | Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis. |
| Protein Name | Beta-1 -4-Galactosyltransferase 5Beta-1 -4-Galtase 5Beta4gal-T5B4gal-T5Beta-1 -4-Galt IiGlucosylceramide Beta-1 -4-GalactosyltransferaseLactosylceramide SynthaseLaccer SynthaseUdp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5Udp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5 |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-913709Reactome: R-HSA-975577Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinTrans Cisternae Of Golgi Stack |
| Alternative Antibody Names | Anti-Beta-1 -4-Galactosyltransferase 5 antibodyAnti-Beta-1 -4-Galtase 5 antibodyAnti-Beta4gal-T5 antibodyAnti-B4gal-T5 antibodyAnti-Beta-1 -4-Galt Ii antibodyAnti-Glucosylceramide Beta-1 -4-Galactosyltransferase antibodyAnti-Lactosylceramide Synthase antibodyAnti-Laccer Synthase antibodyAnti-Udp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5 antibodyAnti-Udp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5 antibodyAnti-B4GALT5 antibody |
Information sourced from Uniprot.org