| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 7 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
B3GNT7 |
| Gene ID: |
93010 |
| Uniprot ID: |
B3GN7_HUMAN |
| Specificity: |
This antibody detects endogenous levels of B3GNT7 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human B3GNT7 |
| Function | N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non-reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units ->3Galbeta1->4(6-sulfoGlcNAcbeta)1-> and ->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1-> within keratan sulfate polymer. Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency. May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion. |
| Protein Name | Udp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 7Bgnt-7Beta-1 -3-Gn-T7Beta-1 -3-N-Acetylglucosaminyltransferase 7Beta3gn-T7 |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Udp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 7 antibodyAnti-Bgnt-7 antibodyAnti-Beta-1 -3-Gn-T7 antibodyAnti-Beta-1 -3-N-Acetylglucosaminyltransferase 7 antibodyAnti-Beta3gn-T7 antibodyAnti-B3GNT7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
