Anti-B3GNT7 antibody (STJA0009439)

SKU:
STJA0009439
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 7 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: B3GNT7
Gene ID: 93010
Uniprot ID: B3GN7_HUMAN
Specificity: This antibody detects endogenous levels of B3GNT7 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human B3GNT7
Function N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non-reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units ->3Galbeta1->4(6-sulfoGlcNAcbeta)1-> and ->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1-> within keratan sulfate polymer. Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency. May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion.
Protein Name Udp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 7
Bgnt-7
Beta-1 -3-Gn-T7
Beta-1 -3-N-Acetylglucosaminyltransferase 7
Beta3gn-T7
Database Links Reactome: R-HSA-2022854
Reactome: R-HSA-913709
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Udp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 7 antibody
Anti-Bgnt-7 antibody
Anti-Beta-1 -3-Gn-T7 antibody
Anti-Beta-1 -3-N-Acetylglucosaminyltransferase 7 antibody
Anti-Beta3gn-T7 antibody
Anti-B3GNT7 antibody

Information sourced from Uniprot.org

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