| Short Description : | Rabbit polyclonal anti-Ataxin-3-like protein (99-149 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATXN3L |
| Gene ID: | 92552 |
| Uniprot ID: | ATX3L_HUMAN |
| Immunogen: | Synthesized peptide derived from the human ATX3L at the amino acid range 99-149 |
| Immunogen Region: | 99-149 aa |
| Specificity: | This antibody detects endogenous levels of ATX3L at Human |
| Function | Deubiquitinating enzyme that cleaves both 'Lys-48'-linked and 'Lys-63'-linked poly-ubiquitin chains (in vitro). Acts as a deubiquitinating enzyme for the transcription factor KLF5, playing a role in the regulation of KLF5 stability. |
| Protein Name | Ataxin-3-Like ProteinMachado-Joseph Disease Protein 1-Like |
| Database Links | Reactome: R-HSA-5689877 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ataxin-3-Like Protein antibodyAnti-Machado-Joseph Disease Protein 1-Like antibodyAnti-ATXN3L antibodyAnti-ATX3L antibodyAnti-MJDL antibody |
Information sourced from Uniprot.org
