Anti-ATRIP antibody [R03-9J5] (STJA0037436)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human ATRIP
General Information
| Short Description | Rabbit monoclonal anti-ATRIP for use in WB, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-9J5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | ATRIP |
| Gene ID | 84126 |
| Uniprot ID | ATRIP_HUMAN |
| Immunogen | A synthesized peptide derived from human ATRIP |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylated by ATR. |
| Function | Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. |
| Protein Name | Atr-Interacting ProteinAtm And Rad3-Related-Interacting Protein |
| Database Links | Reactome: R-HSA-176187Reactome: R-HSA-5685938Reactome: R-HSA-5693607Reactome: R-HSA-5693616Reactome: R-HSA-6783310Reactome: R-HSA-6804756Reactome: R-HSA-69473Reactome: R-HSA-9709570 |
| Cellular Localisation | NucleusRedistributes To Discrete Nuclear Foci Upon Dna Damage |
| Alternative Antibody Names | Anti-Atr-Interacting Protein antibodyAnti-Atm And Rad3-Related-Interacting Protein antibodyAnti-ATRIP antibodyAnti-AGS1 antibody |
Information sourced from Uniprot.org