| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
ATP6V1H |
| Gene ID: |
51606 |
| Uniprot ID: |
VATH_HUMAN |
| Immunogen Region: |
254-483 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 254-483 of human ATP6V1H (NP_057025.2). |
| Immunogen Sequence: |
PQMCEHLRRYNIIPVLSDIL QESVKEKVTRIILAAFRNFL EKSTERETRQEYALAMIQCK VLKQLENLEQQKYDDEDISE DIKFLLEKLGESVQDLSSFD EYSSELKSGRLEWSPVHKSE KFWRENAVRLNEKNYELLKI LTKLLEVSDDPQVLAVAAHD VGEYVRHYPRGKRVIEQLGG KQLVMNHMHHEDQQVRYNAL LAVQKLMVHNWEYLGKQLQS EQPQTAAARS |
| Tissue Specificity | Widely expressed. |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit H is essential for V-ATPase activity, but not for the assembly of the complex. Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes. |
| Protein Name | V-Type Proton Atpase Subunit HV-Atpase Subunit HNef-Binding Protein 1Nbp1Protein Vma13 HomologV-Atpase 50/57 Kda SubunitsVacuolar Proton Pump Subunit HVacuolar Proton Pump Subunit Sfd |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-167590Reactome: R-HSA-182218Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9636467Reactome: R-HSA-9639288Reactome: R-HSA-983712Reactome: R-HSA-9857377 |
| Cellular Localisation | Cytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit H antibodyAnti-V-Atpase Subunit H antibodyAnti-Nef-Binding Protein 1 antibodyAnti-Nbp1 antibodyAnti-Protein Vma13 Homolog antibodyAnti-V-Atpase 50/57 Kda Subunits antibodyAnti-Vacuolar Proton Pump Subunit H antibodyAnti-Vacuolar Proton Pump Subunit Sfd antibodyAnti-ATP6V1H antibodyAnti-CGI-11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
