| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | ATP6V1F |
| Gene ID: | 9296 |
| Uniprot ID: | VATF_HUMAN |
| Immunogen Region: | 1-119 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human ATP6V1F (NP_004222.2). |
| Immunogen Sequence: | MAGRGKLIAVIGDEDTVTGF LLGGIGELNKNRHPNFLVVE KDTTINEIEDTFRQFLNRDD IGIILINQYIAEMVRHALDA HQQSIPAVLEIPSKEHPYDA AKDSILRRARGMFTAEDLR |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. |
| Protein Name | V-Type Proton Atpase Subunit FV-Atpase Subunit FV-Atpase 14 Kda SubunitVacuolar Proton Pump Subunit F |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembranePeripheral Membrane ProteinClathrin-Coated Vesicle Membrane |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit F antibodyAnti-V-Atpase Subunit F antibodyAnti-V-Atpase 14 Kda Subunit antibodyAnti-Vacuolar Proton Pump Subunit F antibodyAnti-ATP6V1F antibodyAnti-ATP6S14 antibodyAnti-VATF antibody |
Information sourced from Uniprot.org