| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | ATP6V1F |
| Gene ID: | 9296 |
| Uniprot ID: | VATF_HUMAN |
| Immunogen Region: | 1-119 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human ATP6V1F (NP_004222.2). |
| Immunogen Sequence: | MAGRGKLIAVIGDEDTVTGF LLGGIGELNKNRHPNFLVVE KDTTINEIEDTFRQFLNRDD IGIILINQYIAEMVRHALDA HQQSIPAVLEIPSKEHPYDA AKDSILRRARGMFTAEDLR |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. |
| Protein Name | V-Type Proton Atpase Subunit F V-Atpase Subunit F V-Atpase 14 Kda Subunit Vacuolar Proton Pump Subunit F |
| Database Links | Reactome: R-HSA-1222556 Reactome: R-HSA-77387 Reactome: R-HSA-917977 Reactome: R-HSA-9639288 Reactome: R-HSA-983712 |
| Cellular Localisation | Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle Membrane Peripheral Membrane Protein Clathrin-Coated Vesicle Membrane |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit F antibody Anti-V-Atpase Subunit F antibody Anti-V-Atpase 14 Kda Subunit antibody Anti-Vacuolar Proton Pump Subunit F antibody Anti-ATP6V1F antibody Anti-ATP6S14 antibody Anti-VATF antibody |
Information sourced from Uniprot.org