Anti-ATP6V0C antibody (N-Term) (STJA0010320)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human N-ternal VATL
General Information
| Short Description | Rabbit polyclonal anti-V-type proton ATPase 16 kDa proteolipid subunit c (N-Term) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP6V0C |
| Gene ID | 527 |
| Uniprot ID | VATL_HUMAN |
| Immunogen | Synthesized peptide derived from human N-ternal VATL |
| Immunogen Region | N-Term |
| Specificity | This antibody detects endogenous levels of VATL at Human, Mouse, Rat |
Additional Info
| Function | Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments, and in some cell types, it is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. |
| Protein Name | V-Type Proton Atpase 16 Kda Proteolipid Subunit CV-Atpase 16 Kda Proteolipid Subunit CVacuolar Proton Pump 16 Kda Proteolipid Subunit C |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-6798695Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712Reactome: R-HSA-9857377 |
| Cellular Localisation | Cytoplasmic VesicleClathrin-Coated Vesicle MembraneMulti-Pass Membrane ProteinSecretory VesicleSynaptic Vesicle Membrane |
| Alternative Antibody Names | Anti-V-Type Proton Atpase 16 Kda Proteolipid Subunit C antibodyAnti-V-Atpase 16 Kda Proteolipid Subunit C antibodyAnti-Vacuolar Proton Pump 16 Kda Proteolipid Subunit C antibodyAnti-ATP6V0C antibodyAnti-ATP6C antibodyAnti-ATP6L antibodyAnti-ATPL antibody |
Information sourced from Uniprot.org