| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
ATP5MC3 |
| Gene ID: |
518 |
| Uniprot ID: |
AT5G3_HUMAN |
| Immunogen Region: |
50 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human ATP5G3 (NP_001002258.1). |
| Immunogen Sequence: |
NGVSQLIQREFQTSAISRDI DTAAKFIGAGAATVGVAGSG AGIGTVFGSLIIGYARNPSL KQQLFSYAILGFALSEAMGL FCLMVAFLILFAM |
| Post Translational Modifications | Trimethylated by ATPSCKMT at Lys-110. Methylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. |
| Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. |
| Protein Name | Atp Synthase F(0 Complex Subunit C3 - MitochondrialAtp Synthase Lipid-Binding ProteinAtp Synthase Membrane Subunit C Locus 3Atp Synthase Proteolipid P3Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit C3Atpase Protein 9Atpase Subunit C |
| Database Links | Reactome: R-HSA-163210Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp Synthase F(0 Complex Subunit C3 - Mitochondrial antibodyAnti-Atp Synthase Lipid-Binding Protein antibodyAnti-Atp Synthase Membrane Subunit C Locus 3 antibodyAnti-Atp Synthase Proteolipid P3 antibodyAnti-Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit C3 antibodyAnti-Atpase Protein 9 antibodyAnti-Atpase Subunit C antibodyAnti-ATP5MC3 antibodyAnti-ATP5G3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
