| Function | Subunit c, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). With the subunit a (MT-ATP6), forms the proton-conducting channel in the F(0) domain, that contains two crucial half-channels (inlet and outlet) that facilitate proton movement from the mitochondrial intermembrane space (IMS) into the matrix. Protons are taken up via the inlet half-channel and released through the outlet half-channel, following a Grotthuss mechanism. |
| Protein Name | Atp Synthase F(0 Complex Subunit C1 - MitochondrialAtp Synthase Lipid-Binding ProteinAtp Synthase Membrane Subunit C Locus 1Atp Synthase Proteolipid P1Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit C1Atpase Protein 9Atpase Subunit CProton-Conducting Channel - Atp Synthase F(0 Complex Subunit C |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-163210Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp Synthase F(0 Complex Subunit C1 - Mitochondrial antibodyAnti-Atp Synthase Lipid-Binding Protein antibodyAnti-Atp Synthase Membrane Subunit C Locus 1 antibodyAnti-Atp Synthase Proteolipid P1 antibodyAnti-Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit C1 antibodyAnti-Atpase Protein 9 antibodyAnti-Atpase Subunit C antibodyAnti-Proton-Conducting Channel - Atp Synthase F(0 Complex Subunit C antibodyAnti-ATP5MC1 antibodyAnti-ATP5G1 antibody |
Information sourced from Uniprot.org
