| Tissue Specificity | Expressed predominantly in the adult and fetal central nervous system. Measurable expression in all tissues examined, although expression in adult brain is at least 50-fold higher than in other tissues. Detected predominantly in pyramidal neurons in the cerebral cortex and the hippocampus of the brain. Expressed in upper and lower motor neurons (at protein level). |
| Function | GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development. |
| Protein Name | Atlastin-1Brain-Specific Gtp-Binding ProteinGtp-Binding Protein 3Gbp-3Hgbp3Guanine Nucleotide-Binding Protein 3Spastic Paraplegia 3 Protein A |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneCell ProjectionAxonLocalizes To Endoplasmic Reticulum Tubular Network |
| Alternative Antibody Names | Anti-Atlastin-1 antibodyAnti-Brain-Specific Gtp-Binding Protein antibodyAnti-Gtp-Binding Protein 3 antibodyAnti-Gbp-3 antibodyAnti-Hgbp3 antibodyAnti-Guanine Nucleotide-Binding Protein 3 antibodyAnti-Spastic Paraplegia 3 Protein A antibodyAnti-ATL1 antibodyAnti-GBP3 antibodyAnti-SPG3A antibody |
Information sourced from Uniprot.org
