Anti-ATAD3B antibody (STJA0007091)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ATAD3A/B
General Information
| Short Description | Rabbit polyclonal anti-ATPase family AAA domain-containing protein 3B for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATAD3B |
| Gene ID | 83858 |
| Uniprot ID | ATD3B_HUMAN |
| Immunogen | Synthesized peptide derived from human ATAD3A/B |
| Specificity | This antibody detects endogenous levels of ATAD3A/B at Human |
Additional Info
| Function | May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. May act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes. |
| Protein Name | Atpase Family Aaa Domain-Containing Protein 3bAaa-Tob3 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinHas Been Found To Co-Purify With NucleoidsSince It Does Not Face The Mitochondrial MatrixThe Association With Nucleoids Could Be Mediated By Atad3a |
| Alternative Antibody Names | Anti-Atpase Family Aaa Domain-Containing Protein 3b antibodyAnti-Aaa-Tob3 antibodyAnti-ATAD3B antibodyAnti-KIAA1273 antibodyAnti-TOB3 antibody |
Information sourced from Uniprot.org