Anti-ASS1 antibody (1-100) [S0MR] (STJ11102420)

Name: Anti-ASS1 antibody (1-100) [S0MR] (STJ11102420)
SKU: STJ11102420
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11102420

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Short Description	Rabbit monoclonal ASS1 (1-100) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S0MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ASS1
Gene ID	445
Uniprot ID	ASSY_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MSSKGSVVLAYSGGLDTSCI LVWLKEQGYDVIAYLANIGQ KEDFEEARKKALKLGAKKVF IEDVSREFVEEFIWPAIQSS ALYEDRYLLGTSLARPCIAR
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ASS1 (P00966).

Tissue Specificity	Expressed in adult liver.
Post Translational Modifications	Acetylated by CLOCK in a circadian manner which negatively regulates its enzyme activity. Deacetylated by histone deacetylases.
Function	One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Protein Name	Argininosuccinate Synthase Citrulline--Aspartate Ligase
Database Links	Reactome: R-HSA-70635
Cellular Localisation	Cytoplasm Cytosol
Alternative Antibody Names	Anti-Argininosuccinate Synthase antibody Anti-Citrulline--Aspartate Ligase antibody Anti-ASS1 antibody Anti-ASS antibody

Information sourced from Uniprot.org