Anti-ASCC1 antibody (289-339 aa) (STJ194445)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ASCC1 at the amino acid range 289-339
General Information
| Short Description | Rabbit polyclonal anti-Activating signal cointegrator 1 complex subunit 1 (289-339 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ASCC1 |
| Gene ID | 51008 |
| Uniprot ID | ASCC1_HUMAN |
| Immunogen | Synthesized peptide derived from the human ASCC1 at the amino acid range 289-339 |
| Immunogen Region | 289-339 aa |
| Specificity | This antibody detects endogenous levels of ASCC1 at Human/Mouse |
Additional Info
| Function | Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction. |
| Protein Name | Activating Signal Cointegrator 1 Complex Subunit 1Asc-1 Complex Subunit P50Trip4 Complex Subunit P50 |
| Database Links | Reactome: R-HSA-112126 |
| Cellular Localisation | NucleusNucleus SpeckleColocalizes With Prpf8 In Nuclear Speckles In The Absence Of Dna Damage |
| Alternative Antibody Names | Anti-Activating Signal Cointegrator 1 Complex Subunit 1 antibodyAnti-Asc-1 Complex Subunit P50 antibodyAnti-Trip4 Complex Subunit P50 antibodyAnti-ASCC1 antibodyAnti-CGI-18 antibody |
Information sourced from Uniprot.org