| Host: | Rabbit |
| Applications: | IHC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Ankyrin Repeat And Socs Box Protein 6 for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: | Antigen affinity purification |
| Concentration: | 1.32 mg/mL |
| Dilution Range: | IHC 1:50-1:300 |
| Storage Instruction: | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | ASB6 |
| Gene ID: | 140459 |
| Uniprot ID: | ASB6_HUMAN |
| Immunogen: | Fusion protein of human ASB6 |
| Post Translational Modifications | Ubiquitinated by RNF41.leading to proteasomal degradation. |
| Function | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the regulation of cell proliferation and autophagy by promoting the ubiquitination and degradation of SQSTM1. |
| Protein Name | Ankyrin Repeat And Socs Box Protein 6Asb-6 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ankyrin Repeat And Socs Box Protein 6 antibodyAnti-Asb-6 antibodyAnti-ASB6 antibody |
Information sourced from Uniprot.org
